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Food and Drug Administration) (2019)

Another study showed that GEN improved liver necrosis induced by toxic doses of paracetamol more markedly than SL (Mustika and Achmad, 2014)

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In humans, acetaminophen use during pregnancy, especially for durations of more than four weeks, is associated with an increased risk of having male children with an undescended testicle at birth (26)

Finally, products of the phase II metabolism are transported into the bile ducts via phase III metabolism, which is regulated by a number of transporters localized primarily to the biliary canaliculus