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As shown in Figure S7, key differences in the binding modes of non-cyclic ligand 7a and cyclic ligands 7b 7i were revealed through analysis of their intermolecular interaction profiles, with 7a forming numerous but low-frequency contacts - likely due to its flexible warhead - while the more rigid cyclic ligands engaged in fewer but higher-frequency interactions, indicating slightly greater binding specificity and complex stability

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Deficiencies or imbalances under light stress commonly manifest as chlorosis and reduced photosynthetic performance (Anderson et al

236 Beyond specific site modifications, altering the sugar ring provides another NADs design strategy