That got the attention of cardiologists everywhere
Between February 2024 and October 2025, the number of American adults who reported taking GLP-1s for weight loss more than doubled, constituting roughly 12% of the population, according to Gallup polling
At the heart of this intricate system lies Glucagon-Like Peptide-1 (GLP-1), a hormone pivotal in regulating blood sugar, appetite, and overall metabolic function
Diabetes Care 39:e199e200 Kelly RP, Garhyan P, Raddad E et al (2015) Short-term administration of the glucagon receptor antagonist LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes
People with specific medical conditions, such as a history of pancreatitis or severe gastrointestinal disorders, should discuss these with their provider to weigh the risks and benefits