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Yes, when monitored by a healthcare provider

In the guidelines issued by the American Association of Clinical Endocrinologists (AACE), American Diabetes Association (ADA) and Chinese Diabetes Society, GLP-1RAs and SGLT-2is are the choice drugs in the case of metformin failure (Garber et al., 2019

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Reducing exposure to environmental pollutants and toxins, adopting healthy lifestyle habits, and improving dietary choices can significantly reduce ROS levels and improve sperm quality