A physician would take extra care, or advise against this class entirely, for people with certain thyroid conditions, a history of pancreatitis, significant gastrointestinal disease, or those who are pregnant or trying to conceive
"We've known for several years now that obstructive sleep apnea is a factor in NAION," he says
Protects neurons from oxidative stress, important in neurodegenerative diseases like Parkinsons and Alzheimers
This may lead to many of the same reported side effects as above, but may also come with complications like dehydration or malnutrition if left untreated
A 2003 study by Khavinson's team lengthened telomeres in human cells, and in 2025 an independent group at Brunel University London reported dose-dependent telomere extension in normal human cells