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Acknowledgements The authors acknowledge the support of grants from Inserm, CNRS, Universit Paris Cit, Agence Nationale de la Recherche (ANR), Socit Francophone du Diabte (SFD), Fondation pour la Recherche Mdicale (FRM), the Dutch Organization for Scientific Research (ZonMW) and DiabetesFonds

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The campaign targets 1624-year-olds after data revealed: An eight-fold increase in people seeking treatment for ketamine use since 2015 5,448 drug poisoning deaths in England and Wales in 2023 - the highest since records began The initiative warns that recreational drug use can cause irreparable bladder damage, poisoning, and even death, with particular risks from synthetic opioids hidden in fake medicines and THC vapes containing synthetic cannabinoids like spice

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