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Ferroptosis: A critical player and potential therapeutic target in traumatic brain injury and spinal cord injury

Discovery of BMS-986318, a potent nonbile acid FXR agonist for the treatment of nonalcoholic steatohepatitis

Methods We systematically reviewed PubMed, Embase, Cochrane, Web of Science (through September 2025) for randomized trials and observational studies evaluating oral semaglutide versus placebo in T2D

For instance, sphingolipids, particularly ceramides, have been implicated in trophoblast dysfunction and apoptosis, leading to impaired spiral artery remodeling, a hallmark of early-onset preeclampsia (35)

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