doi: 10.1016/j.freeradbiomed.2010.09.006 225 BarrosoMHandyDECastroR
This creates a vicious cycle: stress raises cortisol, cortisol drives weight gain and appetite, and impaired GLP-1 signaling perpetuates the problem
When a patient is already rethinking their relationship with food, sleep, and movement, it is a short step to ask, Have you thought about how alcohol fits into your health goals? From a metabolic perspective, alcohol adds empty calories, disrupts sleep architecture, worsens insulin resistance, and contributes to fatty liver disease, all of which can undermine the very outcomes GLP-1 therapy is designed to achieve
This dual action sets it apart from other weight management medications by addressing both immediate weight loss needs and long-term health outcomes
Selenium and vitamin E also play supportive roles in glutathione function