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As indicated, the ghrelin-mediated activation of GHS-1Ra leads to activation of PLC with the release of DAG and IP 3 from membrane PIP 2

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Results LAG-1 expression is spatially restricted to stem cells and autonomously required in the germline for the stem cell fate As a first step in examining GLP-1 NotchLAG-1 CSL transcriptional control of the germline stem cell fate, we determined the LAG-1 protein accumulation pattern in both mid-L4 and adult hermaphrodites, stages typically analyzed in studies of germline development

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Sivagami G, Vinothkumar R, Preethy CP, Riyasdeen A, Akbarsha MA, Menon VP, et al