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Design, synthesis and biological evaluation of hetero-aromatic moieties substituted pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors

Besides, considering the cuprizone effect on schizophrenia and thereby antipsyhotics in cuprizone model (73) BPC 157 also counteracts amphetamine toxicity, both acute and chronic (74, 75), like MPTP-toxicity and lethality (76), as well as catalepsy that may be produced by various neuroleptics (77)