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Topiramate contributes paresthesia (tingling in hands and feet), taste changes (especially carbonated beverages tasting flat or metallic), cognitive slowing, word-finding difficulty, and kidney stone risk

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Lameire N, Van Biesen W, Vanholder R (2005) Acute renal failure

Safety Considerations for Adults with Lymphoproliferative Disorders For adults with existing lymphoproliferative disorders , the decision to initiate or continue GLP-1 agonist therapy requires individualised clinical assessment