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CD 8+ cytotoxic T lymphocytes, activated by antigens presented by oligodendrocytes and neurons, are implicated in demyelination and axonal/neuronal damage [268]

Nov 1999;41(5 Pt 2):887-889

Furthermore, VEGF is believed to play a key role in traumatic brain injury (TBI), particularly in scenarios where Apolipoprotein E (ApoE) expression is absent (Genovese and Impellizzeri 2022)

This guide covers the mechanism, what the animal research actually shows, and the critical limitations any rational evaluation must account for