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But once you prime it and take your first dose, the 56-day room temperature clock starts

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Protocol adjustments Initial protocols sometimes need adjustment

This includes clear liquids for a few days, progressing to pureed foods for several weeks before returning to solid foods

Burning has no relationship to medication efficacy

Also, the rare, but serious, side effect of diabetic ketoacidosis can hinder their use particularly in those with longer diabetes duration and limited beta-cell reserves