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In the same trial, people on CagriSema lost an average of about 23% of their body weight over 68 weeks when measuring the effect assuming full adherence, or about 21% when accounting for all participants regardless of whether they completed treatment

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This alteration of the endothelium-mediated vasorelaxation is also observed in healthy subjects affected with moderate hyperhomocysteinemia (Tawakol et al, 1997

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