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Gastroenterology 151:5169.e14
It is likely that somatostatin may have an additional sst 2 -mediated inhibitory action at the pituitary level where ACTH-secreting cells express the sst 2 (Day et al., 1998)
Initial testing: Do CBC and B12 tests before starting treatment and again after the first dose
[PMC free article] [PubMed] [Google Scholar] 13.Menter MA, Caveney SW, Gottschalk RW
Theoretical concerns are not proof of harm, but they identify areas off-target SAM effects, signalling-pathway impacts, and uncharacterised interactions that require study before any conclusion about human safety could be drawn
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