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3,4 Further cytokine production can occur as the LL37/DNA complex can act as an auto-antigen by fitting into the groove of human leukocyte antigen-Cw6 that is then presented to the T-lymphocyte

Transient and mostly mild-to-moderate gastrointestinal symptoms were the most frequently reported AE and occurred more frequently with the 4 mg starting dose groups rather than the 2 mg starting dose groups [67]

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Human muscle cells Meanwhile, A pilot study treated cultured myoblasts obtained from women, but this ex-vivo work did not establish human therapeutic safety or efficacy