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Lanifibranor, a triple PPAR agonist targeting , , and subtypes, was chemically conjugated to a dipeptidyl peptidase-4 (DPP4)-protected incretin co-agonist backbone (MAR709)

ELISA Following the manufacturers instructions, specific enzyme-linked immunosorbent assay (ELISA) kits were used to detect the levels of luteinizing hormone (LH) (JM-11607M2, Jingmei Biological Technology, Jiangsu, China), estradiol (E2) (JM-02849M2, Jingmei Biological Technology, Jiangsu, China), follicle stimulating hormone (FSH) (JM-02838M2, Jingmei Biological Technology, Jiangsu, China), and progesterone (PROG) (JM-02851M2, Jingmei Biological Technology, Jiangsu, China) in the serum of E13.5 pregnant mice