As far back as the 1970s, there were case reports in the literature of B12 deficiency associated with metformin use, with several observational studies reporting the same, but very little in the way of high-quality, well-powered, prospective studies
These outcomes reflect observed biomarker and pathway changes under controlled conditions and are not established therapeutic claims
Why does that matter for weight loss
The treatments deliver essential nutrients directly to the body, enabling faster absorption and more effective results than oral supplements
Know when to seek prompt care o Contact your clinician if you notice fatigue, bruising, jaundice, abdominal pain, or unexplained weight loss