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1.2 Pathogenesis of hashimotos thyroiditis Hashimotos thyroiditis (HT) is characterized by dense lymphocytic infiltration of the thyroid gland, leading to progressive destruction of follicular cells

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They also function to disrupt the positive feedback mechanism involving local prostaglandin production that is responsible for further increasing estrogen levels in ectopic endometrial cells (34)

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Metabolic reprogramming of macrophages by biomimetic melatonin-loaded liposomes effectively attenuates acute gouty arthritis in a mouse model