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After accounting for weight loss, the researchers found that in the semaglutide group, being older, female or eating less protein was linked to greater muscle loss

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Retatrutide is currently being studied for its ability to help: Reduce hunger Increase satiety Improve metabolic signaling Support fat loss through multiple hormonal pathways In a Phase 2 obesity trial published in The New England Journal of Medicine, retatrutide produced substantial weight loss over 48 weeks, with the highest-dose group showing mean weight loss of 24.2%

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