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The core pathophysiological alteration in PMOS involves dysfunction of the hypothalamic-pituitary-ovarian axis, primarily characterized by dysregulated GnRH release and excessive pulsatile secretion of LH

O'Harte, Ulster University, United Kingdom Jobichen Chacko, Australian National University, Australia Sapana Kushwaha, National Institute of Pharmaceutical Education and Research, India Updates Copyright 2023 Saini, Sharma and Khan

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