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Such decrease, possibly due to interference with B12 absorption from the B12-intrinsic factor complex, may be associated with anemia but appears to be rapidly reversible with discontinuation of metformin or vitamin B12 supplementation

Cancer Biol Ther 7(1):103-8, 2008

Some clinical studies have found that GHK-Cu-based creams produced results comparable to vitamin C and retinoids, without causing irritation

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