Approved in 2022 for diabetes (brand Mounjaro), tirzepatide produced extraordinary results in weight loss up to ~22% in obese participants at the highest dose in a phase 3 trial ( [137] )
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The graph represents the mean percent biotin-GFP (SEM, n = 6 independent experiments), normalized to total GFP band intensity, and relative to the H 2 O treated control group
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