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A decreased concentration of melatonin in the follicular fluid could be responsible for anovulation and poor quality oocytes in a patient with PCOS and, therefore, melatonin treatment can improve the quality of oocytes during follicular maturation [114]

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Where appropriate, data from independent experiments were pooled to obtain sufficient statistical power

The WT mice had considerably less DNA adducts (molecules that are strongly bonded to DNA that can lead to DNA breaks and mutations) than the KO mice