Looking beyond the horizons of todays obesity therapeutics with the goal of achieving healthier, sustainable outcomes
Non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin (ASA) reduce inflammation by inhibiting the synthesis of prostaglandins (PGs) and induce apoptosis in a variety of cancer cells [5], [6], [7].Tumor cells are known to develop resistance towards therapeutic drugs and irradiation due to inhibition of apoptotic stimuli in these cells
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In MPTP-induced monkey model of PD, clioquinol significantly alleviated both dyskinesia and non-motor impairments, concomitant with a reduction in iron accumulation and ROS levels in the SN (228)