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The broader systematic review of GLP-1 drugs in pain conditions [9] and the 2025 comprehensive review in the Journal of Headache and Pain [1] both conclude that the mechanistic case is plausible and interesting, but that human clinical trials with pain as the primary outcome are needed before we can make firm recommendations
Weight benefit: Trials reported weight loss rather than the weight gain that usually accompanies intensified insulin therapy a distinguishing feature of the amylin mechanism [4]
Protein Cell 6 , 628637 (2015 Zhao, X
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Interfering with the glycolytic pathway in PC from the perspective of TME may solve challenges associated with postoperative chemotherapeutic resistance, immune tolerance and ineffectiveness of radiotherapy
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