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56 These studies suggest that GTP hydrolysis by ZNG1 simulates metalation of the empty METAP1 active site above that which could be obtained with GMPPNP or the OFF-state product GDP, consistent with the mechanistic model shown (Figure 51A)

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Interactions between subunits of the Mediator complex with gene-specific transcription factors

Similar content being viewed by others Introduction Human skin is an extensive and complex organ responsible for the numerous functions essential for human functioning, including thermoregulation, water management, but also receiving stimuli from the surrounding environment, as well as immune reactions and protection against harmful xenobiotics and external physical factors 1