Disulfide bonds are relatively stable under physiological conditions but undergo selective cleavage in the tumor microenvironment (TME), minimizing premature drug release [53]
A report has shown that KDM3B, a histone H3 lysine 9 demethylase, can protect against erastin-induced ferroptosis and is thus considered a potential epigenetic regulator of ferroptosis (Wang et al., 2020)
Physiological and biochemical responses of mungbean (Vigna radiata L
Mitochondria generate the majority of cellular ROS as a byproduct of oxidative phosphorylation, and mitochondrial GSH is the primary defense against this constant oxidative burden
Rodina A, Wang T, Yan P, Gomes ED, Dunphy MP, Pillarsetty N, Koren J, Gerecitano JF, Taldone T, Zong H, et al