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Effect of insulinotropic agent nateglinide on Kv and Ca(2+) channels in pancreatic beta-cell

The word lipotropic refers to compounds that are involved in the way the body processes fats

Case Rep Hematol 2015:180526 Azarkeivan A, Ansari S, Ahmadi MH, Hajibeigy B, Maghsudlu M, Nasizadeh S, Shaigan M, Toolabi A, Salahmand M (2011) Blood transfusion and alloimmunization in patients with thalassemia: multicenter study

This PEN2-v-ATPase-Ragulator pathway (Figure 1) links metformin to lysosomal nutrient sensing rather than mitochondrial stress, offering a potentially safer mode of AMPK activation

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