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Purpose-formulated topical preparations or sterile application techniques would be preferable to potentially introducing contaminants to open wounds

It is used to treat conditions such as toothache, headache, arthritis, back pain and menstrual cramps

Insurance coverage (where available for brand-name GLP-1s) can significantly reduce costs but may involve prior authorization, step therapy requirements, and coverage limitations

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Gopal Grandhige, MD, FACS, Board-Certified Surgeon Last Reviewed: May 15, 2026 Hexarelin and ipamorelin are both synthetic growth hormone-releasing peptides, but they are not interchangeable