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Thus, identifying novel therapeutics that target multiple pathways and genes associated with AD represents a promising strategy for treatment

In AD, GSH depletion impacts microglia function and reduces -amyloid clearance

Gastrointestinal side effects were the most commonly reported adverse events, were generally mild to moderate in severity, and usually occurred during the dose escalation period

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6.4 Incretin Receptor Activation Normalizes Cell Respiration, Oxidative Phosphorylation, and Glycolysis in Neurons Using the Seahorse analysis tool, which can measure glucose turnover, oxygen consumption, and ATP production, it was found that GLP-1 can enhance glycolytic activity in astrocyte cell culture