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The MS pulldown experiments had identified GPX4 as a target of three out of four SCLAs (SCLA1, SCLA2 and SCLA3
These changes may cause disordered sympathetic and parasympathetic activity (158, 360) as well as PEM and cognitive dysfunction (363)
Furthermore, SNIP1 mutation E366G, found in neurodegenerative disorder patients, reduces association with P-SF3B1, revealing a mechanistic defect caused by the mutation
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In some studies, it even managed to provide these benefits more than vitamin C and retinol
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