How This Works When skeletal muscle is loaded or damaged, the IGF-1 gene is alternatively spliced and the MGF (IGF-1Ec) mRNA is transiently up-regulated first, correlating with markers of satellite-cell activation, before a later switch toward systemic IGF-1Ea associated with differentiation and repair [2]
Inflammopharmacology 32(5):28012820 Mondal M et al (2025) Micro (nano) plastics in the brain: epigenetic perturbations in progression to neurodegenerative diseases
Compensatory insulin receptor (IR) activation on inhibition of insulin-like growth factor-1 receptor (IGF-1R): rationale for cotargeting IGF-1R and IR in cancer
Here is what we know about the connection between PCOS and infertility: Research suggests that up to 7080% of women with PCOS may struggle to conceive Because PCOS also makes weight management harder, addressing insulin resistance can be especially impactful
The older, less used drugs are remarkably more cost-effective: $85,000 for the phentermine drug, and Contrave actually saves money
