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FIGURE 3 2.4 GPX4 Glutathione peroxidase 4 (GPX4) is a membrane-associated phospholipid hydroperoxidase and the only enzyme in the GPX family that directly reduces and destroys lipid hydroperoxides, GPX4 is characterized early and characterizes as the lipid peroxidation inhibitory protein PIP, mainly due to its unique ability ( 2 O 2 and small molecule hydroperoxides, it is also capable of reducing complex lipid compounds such as phospholipids, cholesterol and cholesterol lipid hydroperoxides

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Optic nerve damage: Particularly in individuals with Leber's disease, a hereditary condition that causes retinal degeneration and blindness in children