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Over 5 years the savings to the ministry are $14.2 million

Prednisolone promotes insulin resistance, hepatic glucose production, and fat synthesis, which exacerbate fatty liver No evidence supports corticosteroids as treatment for non-alcoholic fatty liver disease (NAFLD) Lifestyle modification, particularly 710% weight loss, remains the cornerstone of fatty liver management Patients requiring prednisolone for other conditions need careful monitoring of weight, glucose, lipids, and liver function Never stop prescribed corticosteroids abruptly due to risk of serious adrenal insufficiency Table of Contents What Is Fatty Liver Disease and How Is It Treated

33 An in vivo study showed that DMF restored apoptosis sensitivity and inhibited tumour growth and metastasis in cutaneous T-cell lymphoma by targeting NF-B

Wren AM, Seal LJ, Cohen MA, Brynes AE, Frost GS, Murphy KG, Dhillo WS, Ghatei MA, Bloom SR

Eur J Cell Biol (2017) 96:24053