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The role of OS in ALS pathology, whether as a primary cause of disease or a secondary consequence, is now well recognized and many preclinical and clinical studies have consistently demonstrated that the disease is characterized by high levels of OS markers able to induce cellular damage, impaired cell signalling, and finally cell death [25, 86]

[DOI] [PubMed] [Google Scholar] 18.Almiana N., Alsina M.A., Reig F

Psychopharmacology (Berl.) , 235 (10), 30453054

11, 2001, pp

Special Populations: Pregnancy, Pediatrics, and Renal or Hepatic Impairment No safety data exist for BPC-157 in pregnant women, nursing mothers, children, or patients with significant renal or hepatic impairment