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Managing Lasting Body Changes and Planning for Healthy Weight Maintenance Long-term changes to appearance, weight, and metabolism to discuss with your clinician Some people report facial thinning or changes in facial fat with prolonged use

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Dual agonism with GLP-1 and amylin As WL with GLP-1 RA and amylin analogues results both from distinct and overlapping pathways, a combination of these entero-pancreatic hormones may induce a synergistic WL effect [84]