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GLP-1 receptor agonists as a drug class have shown signals of reducing systemic inflammation in clinical trials, including reductions in CRP observed in analyses of the STEP and SUSTAIN trial programmes for semaglutide

doi: 10.1038/nm1010-1097

We appreciate the Administrations commitment to this approach in the aptly named, voluntary BALANCE coverage model for GLP-1s in Medicare and Medicaid