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While there are a number of possible causal factors that may play a role, in the vast majority of cases no single specific cause can be identified

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NAC treatment increased extracellular total antioxidant power and total thiol molecules and enhanced intracellular GSH and patients outcome (106)

In clinical practice, patients typically notice visible improvement at SALT changes of 15-20 percentage points these patients saw a 32.5 percentage point improvement