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The duration of action may shorten

Across GLP-1 trials, roughly 60% of lost weight returns within a year and about 75% over the longer regain curve. Lower-dose maintenance has stronger evidence than complete withdrawal

GLP-1 microdosing is increasingly discussed among women navigating perimenopause and menopause, particularly as hormonal changes begin to influence metabolic regulation and medication tolerance

Speak to Phlo Clinic If the cold sensitivity is significantly affecting your quality of life, our expert clinical team may consider adjusting your dosing schedule

Choose complex carbs like quinoa, brown rice, and whole-grain bread over refined carbs like white bread and sugary snacks