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A histopathologic examination can confirm the MNTI diagnosis by identifying two distinct cell populations: small round cells and larger melanocyte-like cells containing dark brown pigment, set in a fibrillary and collagenized vascular stromal background (Asefa and Hailu 2024)
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Starting at a higher dose or increasing the dose too quickly can increase the risk of adverse events and side effects
These risk factors include: Having these risk factors doesnt guarantee a person will develop lentigo maligna melanoma, but it does increase the risk
JAMA Internal Medicine 2011, 171: 941-954
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