Preserving muscle helps support metabolism, strength, energy levels, and long-term weight maintenance
Mood changes: Some patients describe feeling unlike themselves, even when outside stress hasn't changed
CMN may be further classified based on 6 anatomical sites: bolero (upper back and neck), back (central back, spares buttock and shoulders), bathing trunk (genital area and buttock, not extending to shoulders or neck), breast/belly (isolated to breast and/or abdomen), body extremity (extremity only), and body (most of body with overlap with bolero and bathing trunk)
Firstly, GLP-1 medications directly influence the brains reward and appetite pathways, particularly the hypothalamus, which is involved in weight regulation and food preferences
The first STEP trial (a series of large clinical trials that investigated who semaglutide helps and in what context) reported a 14.9% reduction in body weight over 72 weeks for participants taking 2.4 mg weekly