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(44) reported that the half-maximal effective concentrations (EC50) of GIP with GIPR and of GLP-1 with GLP-1R are 20 pM and 28 pM, respectively, without exhibiting cross-reactivity

Lifestyle Factors: Your everyday habits, including diet, physical activity, and sleep patterns, are crucial contributors to your weight

If patients do not tolerate the maintenance dose 2.4 mg, the dose can be temporarily decreased to 1.7 mg once weekly for maximum 4 weeks

It does not accelerate weight loss

If tiredness persists or worsens, contact your GP or diabetes specialist nurse for assessment, as fatigue may indicate hypoglycaemia, dehydration, nutritional deficiencies, or other underlying conditions requiring investigation