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For example, studies using rodents and primary neuron cultures have demonstrated that sulforaphane upregulates key antioxidant enzymes, such as glutathione-S-transferase (GST), NAD(P)H oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1), leading to reduced oxidative burden in both neurodevelopmental and neurodegenerative models (Innamorato et al., 2008

None of the GLP-1 medications prescribed in the NYU cohort were prescribed by rheumatologists

doi:10.1177/25424823251388650 American Institute for Cancer Research

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Due to the large number of medications tested only in preclinical models, the review will center on potential medications that have progressed to clinical trials (Table 1)