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GLP-1 receptor activation preserves cardiac performance by activating multiple pro-survival kinases and modulating cell apoptosis and energy utilization (5-7), and exendin-4 (a long-acting GLP-1 analogue)-mediated GLP-1 receptor activation in models of MI inhibits cardiac remodeling by mitigating oxidative stress-induced injury (6) and attenuating interstitial fibrosis (4)

And, yes, if you eat enough of them, there is a risk of you turning a bit orange

Less movement means less frequent bowel movements

Tirzepatide similarly reduced energy intake early in treatment and was associated with marked decreases in appetite, food cravings, and overeating tendencies [94]

Having a backup plan prevents reverting to old patterns