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You start to gain weight that you cant control, weight that isnt responding the way youre used to

8): Activates PGC1-mediated mitochondrial thermogenesis, outperforming BBR in reducing adiposity indices (Lees index, eWAT or BAT mass) and alleviating dyslipidemia in HFD-fed obese mice at equimolar doses [214]

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The escalation schedule increases the dose every 4 weeks up to the 2.4 mg maintenance dose