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They must ensure nutritional needs are met and they maintain a healthy body weight, especially in patients with diabetes, where balanced nutrition plays a critical role in disease management

Thus, target engagement studies can provide valuable information about the extent to which drugs are hitting their desired targets, and in the case of dual and triple agonists, the relative contributions of each component which can be used to better understand pharmacological effects

Incretin agonism reduces appetite, promotes insulin release, and slows gastric transit, which together lead to profound weight loss with improvements in metabolism 16

Its metabolic activities include antioxidant and anti-inflammatory

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