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And it is not just a medical gray zone
Cosmetic use has decades of informal exposure, but no systematic long-term adverse-event surveillance has been published
C., Mazumder, K., Bachar, R., Aktar, A
This includes those who: Have heart disease, kidney problems, or overweight Want to avoid weight gain or low blood sugar from other diabetes medicines People with overweight or obesity, including: Adults with a body mass index (BMI) of 30 or higher Adults with a BMI of 27 or higher and at least one weight-related health problem (such as high blood pressure or sleep apnea) Adults who have not met weight-loss goals with lifestyle changes alone Adolescents with obesity who qualify for certain GLP-1 medications Who should not receive GLP-1 medications
When supervised by a physician using FDA-approved medications, the risks are generally lower than standard dosing because side effects are dose-dependent
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