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Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions

9,12,17 Remaining questions include the longer-term efficacy and safety of these agents, as well as their efficacy and safety in additional populations, including geriatric patients, pediatric patients, or overweight but non-obese adults without comorbidities

Though unlikely with typical product concentrations that fall within safe parameters, awareness of this risk remains important

The isothiocyanates produced from the breakdown of glucosinolates by the action of the enzyme myrosinase [95] are highly electrophilic, a property of a compound that makes it readily available for the nucleophilic GSH when in the presence of GST [96]