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The evidence from Western blot and mRNA-differential display suggests that cadmium induces AKR1C3 expression at the transcription/translation stage, with this process requiring the mediation of the PI3K/Akt pathway (Lee et al., 2011)

Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response

discontinuation of long-term use has been associated with a withdrawal syndrome with psychotic features

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Structural modifications, such as attaching a lipid chain to a lysine residue, can enhance the peptides effectiveness by prolonging its half-life and bioavailability through non-covalent interactions with albumin